Olimbitsa Procaine Benzylpenicillin Wobayira

Zopangidwa:
Voti ya Eeach ili ndi:
Procaine penicillin bp ……………………… 3,000,000 iu
Benzylpenicillin sodium bp ………………… 1,000,000 iu

Kufotokozera:
Choyera kapena choyera chosayera.
Zotsatira za pharmacological
Penicillin ndi mankhwala ocheperako omwe amachititsa mabakiteriya osiyanasiyana omwe amakhala ndi vuto la gramu komanso cocci ochepa wopanda gramu. mabakiteriya okhudzidwa kwambiri ndi staphylococcus, streptococcus, mycobacterium chifuwa, corynebacterium, clostridium tetanus, actinomycetes, bacillus anthracis, spirochetes, etc. sizimakhudzidwa ndi mycobacteria, mycoplasma, chlamydia, rickettsia, rickettsia, rickettsia, rickettsia, ndi chicketydia, ndi chicketydia, ndi chicketydia, ndi chicketydia, ndi chomera. pharmacokinetics pambuyo pa jekeseni wa mnofu wa procaine penicillin, amayamba kugwira pang'onopang'ono atamasula penicillin ndi hydrolysis yakumalo. nthawi yayitali ndi yayitali, kuchuluka kwa magazi kumakhala kotsika, koma zotsatira zake ndizochulukirapo kuposa penicillin. amangokhala ndi tizilombo toyambitsa matenda omwe amakhudzidwa kwambiri ndi penicillin ndipo sayenera kugwiritsidwa ntchito pochiza matenda oopsa. atatenga penicillin ndi penicillin sodium (potaziyamu) osakanikirana, jekeseni wamagazi amatha kuwonjezeredwa kwakanthawi kochepa, ndikupatsanso zotsatira zosakhalitsa komanso kuchitapo kanthu mwachangu. kuchuluka kwa jakisoni wa procaine penicillin kungayambitse poyizoni.

Pharmacodynamics penicillin ndi bactericidal antiotic okhala ndi antibacterial zochita. ake antibacterial limagwirira makamaka kuletsa kaphatikizidwe wa bakiteriya cell khoma peptidoglycan. mabakiteriya achilengedwe akakulikika agawika mwamphamvu, ndipo khoma la maselo lili mu gawo la biosynthesis. pansi pa penicillin, kapangidwe ka peptidoglycan chatsekedwa ndipo khoma la cell silingapangidwe, ndipo nembanemba ya cell imasweka ndikufa mothandizidwa ndi osmotic.

Penicillin ndi mankhwala ocheperako omwe amachititsa mabakiteriya osiyanasiyana omwe amakhala ndi vuto la gramu komanso cocci ochepa wopanda gramu. mabakiteriya okhudzidwa kwambiri ndi staphylococcus, streptococcus, mycobacterium chifuwa, corynebacterium, clostridium tetanus, actinomycetes, bacillus anthracis, spirochetes, etc. sizimakhudzidwa ndi mycobacteria, mycoplasma, chlamydia, rickettsia, rickettsia, rickettsia, rickettsia, ndi chicketydia, ndi chicketydia, ndi chicketydia, ndi chicketydia, ndi chomera.
pharmacokinetics pambuyo pa jekeseni wa mnofu wa procaine penicillin, amayamba kugwira pang'onopang'ono atamasula penicillin ndi hydrolysis yakumalo. nthawi yayitali ndi yayitali, kuchuluka kwa magazi kumakhala kotsika, koma zotsatira zake ndizochulukirapo kuposa penicillin. amangokhala ndi tizilombo toyambitsa matenda omwe amakhudzidwa kwambiri ndi penicillin ndipo sayenera kugwiritsidwa ntchito pochiza matenda oopsa. atatenga penicillin ndi penicillin sodium (potaziyamu) osakanikirana, jekeseni wamagazi amatha kuwonjezeredwa kwakanthawi kochepa, ndikupatsanso zotsatira zosakhalitsa komanso kuchitapo kanthu mwachangu. kuchuluka kwa jakisoni wa procaine penicillin kungayambitse poyizoni.

Kuyanjana Ndi Mankhwala
1. Penicillin wophatikizidwa ndi aminoglycosides amatha kukulitsa kuchuluka kwa mabakiteriya, motero amakhala ndi mphamvu yolumikizana. 
2. Othandizira okhazikika a bacteriostatic monga macrolides, tetracyclines ndi ma amide alcohols amatha kusokoneza ntchito ya bactericidal ya penicillin ndipo sayenera kugwiritsidwa ntchito limodzi. 
3. Mafuta olemera azitsulo (makamaka mkuwa, zinki, zebaki), ma alcohols, asidi, ayodini, ma oxidant, othandizira kuchepetsa, mankhwala a hydroxy, jakisoni wa glucose kapena tetracycline hydrochloride ingawononge ntchito ya penicillin, komwe ndi kuphwanya malamulo. 
4. Maini ndi penicillin amatha kupanga mchere wopanda mchere, womwe umasintha mayamwidwe. Kuchita uku kungachedwetse mayamwidwe a penicillin, monga procaine penicillin. 
5. Ndipo njira zina zothetsera mankhwala (monga chlorpromazine hydrochloride, lincomycin hydrochloride, norepinephrine tartrate, oxytetracycline hydrochloride, tetracycline hydrochloride, mavitamini a b ndi vitamini c) siziyenera kusakanizika, pena zimatha kutulutsa turpidity, floc kapena mpweya.

Zizindikiro
Amagwiritsidwa ntchito makamaka matenda opatsirana omwe amayamba chifukwa cha penicillin, monga mafinya a chiberekero cha ng ombe, mastitis, zovuta zina, ndi zina zotere.
kugwiritsa ntchito ndi kumwa
Kwa jekeseni wamitsempha. 
Mlingo umodzi, kulemera kwa makilogalamu, magawo 10,000 mpaka 20,000 a mahatchi ndi ng'ombe; Magawo 20,000 mpaka 30,000 a nkhosa, nkhumba, abulu ndi ng'ombe; 30,000 mpaka 40,000 magawo agalu ndi amphaka. kamodzi tsiku lililonse, kwa masiku 2-3. 
onjezerani madzi osalala a jakisoni kuti muimitse kaye musanagwiritse ntchito.

Zochita Zosiyana
1. Njira zoyipa zoyipa ndizoyipa zomwe zimachitika, zomwe zimatha kupezeka mu ziweto zambiri, koma zochulukira ndizochepa. zochita zakomweko zimadziwika ndi edema ndi kupweteka pamalowo jakisoni, ndipo mwadongosolo zimachitika kuti uritisaria ndi zotupa. muzoopsa, zitha kuchititsa mantha kapena kufa. 
2. Nyama zina, zimayambitsa matenda ammimba kawiri.

Chenjezo
1. Izi zimangogwiritsidwa ntchito pochiza matenda opatsirana omwe amayambitsidwa ndi mabakiteriya azovuta kwambiri.
2. Ndiosungunuka pang'ono m'madzi. mukakumana ndi acid, alkali kapena oxidant, imataya mwachangu. chifukwa chake, jakisoni ayenera kukonzekera asanagwiritse ntchito.
3. Yang'anirani kulumikizana ndi kusagwirizana ndi mankhwala ena, kuti zisakhudze phindu.
nthawi yochotsa
Ng'ombe, nkhosa, ndi nkhumba: ma 28; 
Kwa mkaka: maola makumi awiri ndi awiri.

Kusunga:
Losindikizidwa ndikusungidwa pamalo owuma.